endorphin

noun

en·​dor·​phin en-ˈdȯr-fən How to pronounce endorphin (audio)
: any of a group of endogenous peptides (such as enkephalin) found especially in the brain that bind chiefly to opiate receptors and produce some pharmacological effects (such as pain relief) like those of opiates
specifically : beta-endorphin

Did you know?

The word endorphin was coined, back when the substances were discovered in the 1970s, by joining pieces of endogenous and morphine, morphine being a narcotic that closely resembles the endorphins and relieves pain in a similar way. Studies suggest that the pain-relieving practice called acupuncture works by releasing endorphins. Endorphins also seem to play an important role in pregnancy. Though much remains to be learned about the endorphins, the general public seems ready to give them credit for any all-natural high.

Examples of endorphin in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Sunlight, particularly its UV rays, is known to increase endorphin levels in the body by 30 to 50%, according to scientific studies. Tribune Content Agency, Mercury News, 9 May 2025 Submerging for two to ten minutes in water around 50 degrees Fahrenheit can help reduce muscle soreness and inflammation, improve circulation, enhance your focus, and provide an endorphin rush. Izzy Baskette, People.com, 2 May 2025 Running can stimulate the release of endorphins and various neurotransmitters that in turn can boost your mood and make your feel more relaxed. Bruce Y. Lee, Forbes.com, 19 Apr. 2025 Exercise: Exercise, such as walking or running, releases endorphins and provides opportunities to receive sensory input, which may help reduce the need for stimming in some people. Anna Giorgi, Verywell Health, 17 Apr. 2025 See All Example Sentences for endorphin

Word History

Etymology

International Scientific Vocabulary endogenous + morphine

First Known Use

1976, in the meaning defined above

Time Traveler
The first known use of endorphin was in 1976

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Cite this Entry

“Endorphin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/endorphin. Accessed 13 May. 2025.

Medical Definition

endorphin

noun
en·​dor·​phin en-ˈdȯr-fən How to pronounce endorphin (audio)
: any of a group of endogenous peptides (as enkephalin and dynorphin) found especially in the brain that bind chiefly to opiate receptors and produce some of the same pharmacological effects (as pain relief) as those of opiates
specifically : beta-endorphin

More from Merriam-Webster on endorphin

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